Jim DelProposto

Structure-Based Discovery of M-89 as a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein-Protein Interaction

Aguilar A, Zheng K, Xu T, Xu S, Huang L, Fernandez-Salas E, Liu L, Bernard D, Harvey KP, Foster C, McEachern D, Stuckey J, Chinnaswamy K, Delproposto J, Kampf JW, Wang S.

Discovery of ERD-308 as a Highly Potent PROTAC Degrader of Estrogen Receptor (ER)

Hu J, Hu B, Wang M, Xu F, Miao B, Yang CY, Wang M, Liu Z, Hayes DF, Chinnaswamy K, Delproposto J, Stuckey J, Wang S.

Discovery of ARD-69 as a Highly Potent PROTAC Degrader of Androgen Receptor (AR)

Han X, Wang C, Qin C, Xiang W, Fernandez-Salas E, Yang CY, Wang M, Zhao L, Xu T, Chinnaswamy K, Delproposto J, Stuckey J, Wang S.

Structural basis of Toxoplasma gondii perforin-like protein 1 membrane interaction and activity during egress

Guerra AJ, Zhang O, Bahr CME, Huynh MH, DelProposto J, Brown WC, Wawrzak Z, Koropatkin NM, Carruthers VB.

Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors

Yang CY, Phillips JG, Stuckey JA, Bai L, Sun H, Delproposto J, Brown WC, Chinnaswamy K.

D3R grand challenge 2015: Evaluation of protein-ligand pose and affinity predictions

Gathiaka S, Liu S, Chiu M, Yang H, Stuckey JA, Kang YN, Delproposto J, Kubish G, Dunbar JB Jr, Carlson HA, Burley SK, Walters WP, Amaro RE, Feher VA, Gilson MK.

Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 Ectodomain

Yang CY, Delproposto J, Chinnaswamy K, Brown WC, Wang S, Stuckey JA, Wang X.

CSAR Benchmark Exercise 2013: Evaluation of Results from a Combined Computational Protein Design, Docking, and Scoring/Ranking Challenge

Smith RD, Damm-Ganamet KL, Dunbar JB Jr, Ahmed A, Chinnaswamy K, Delproposto JE, Kubish GM, Tinberg CE, Khare SD, Dou J, Doyle L, Stuckey JA, Baker D, Carlson HA.

The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA

Morgan CE, Meagher JL, Levengood JD, Delproposto J, Rollins C, Stuckey JA, Tolbert BS.

Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system

Akey DL, Brown WC, Dutta S, Konwerski J, Jose J, Jurkiw TJ, DelProposto J, Ogata CM, Skiniotis G, Kuhn RJ, Smith JL.

CSAR data set release 2012: ligands, affinities, complexes, and docking decoys

Dunbar JB Jr, Smith RD, Damm-Ganamet KL, Ahmed A, Esposito EX, Delproposto J, Chinnaswamy K, Kang YN, Kubish G, Gestwicki JE, Stuckey JA, Carlson HA.

New ligation-independent cloning vectors compatible with a high-throughput platform for parallel construct expression evaluation using baculovirus-infected insect cells

Brown WC, DelProposto J, Rubin JR, Lamiman K, Carless J, Smith JL.

A nonradioactive high-throughput assay for screening and characterization of adenylation domains for nonribosomal peptide combinatorial biosynthesis

McQuade TJ, Shallop AD, Sheoran A, Delproposto JE, Tsodikov OV, Garneau-Tsodikova S.

Mocr: a novel fusion tag for enhancing solubility that is compatible with structural biology applications

DelProposto J, Majmudar CY, Smith JL, Brown WC.

High-throughput phenotypic profiling of gene-environment interactions by quantitative growth curve analysis in Saccharomyces cerevisiae

Weiss A, Delproposto J, Giroux CN.

Ligand Affinity Measurements for the Community Structure Activity Resource Center

ForteBio Workshop and User Meeting. La Jolla, CA, March 18th, 2014.

CDK2 Ligand Affinity Measurements for the Community Structure Activity Resource Center

Drug Discovery Chemistry. San Diego, CA, April 14th, 2011.

Protein purification tags and uses thereof

United States Patent 8,357,511. Issued August 1, 2008.

Inventors: William Clay Brown, James Delproposto, Janet Smith.

Advanced in Label-Free Assay for Quantitation and Kinetic Characterization

Thursday, March 31st, 2011. Moderator: James DelProposto

Generating Reliable Kinetic Data for Protein-Ligand Interactions

James Delproposto, FortéBio Interactions newsletter. Spring 2011 Vol. 4 Issue 1.